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BIOTECHNOLOGY DIVISION


Background

Formerly part of the Natal Institute of Immunology (NII), a division of the Natal Blood Transfusion Service (NBTS) for more than 30 years, the Biotechnology unit was originally established as a research unit of NBTS.

In April 2000 the newly defined NBI Biotechnology Division, combining the Immunochemistry and ELISA Production Units, was incorporated into the NBI.


Biotechnology Products and Services Profile

NBI Biotechnology's Monoclonal Antibody laboratory produces high affinity mouse monoclonal antibodies suitable for use in either ELISA or Immuno-chromatographic tests, for the detection of infectious diseases. We can also offer custom production of monoclonal antibodies.

The NBI Biotechnology Molecular Biology laboratory produces recombinant proteins that may be used as immunogens, for the production of monoclonal or polyclonal antibodies, or as antigens, in diagnostic tests. Recombinant proteins are expressed in either bacteria (E. coli) or in yeast (Saccharomyces).

The NBI Biotechnology has access to a modern mouse colony facility used for the production of ascites for the NBI Biotech's range of Mabs. Access to this facility via the NBI Biotechnology division is also a service we offer our customers. In addition to mice, rats, rabbits, guinea pigs and primates are housed and fully supported by well-equipped laboratories and theatre facilities.

BIOTECHNOLOGY PRODUCTS

Mab Specificity

Mab Class

HRP II of Plasmodium falciparum

IgG

HRP II of Plasmodium falciparum

IgM

Hepatitis B surface antigen

IgG

Hepatitis B sAg ("d" epitope specific)

IgG

Hepatitis B e-antigen

IgG

Human IgG

IgG

Human IgM

IgG

Human Glycophorin A

IgG

Bovine Glycophorin

IgG

Human alpha fetoprotein

IgG

Human Factor lX

IgG

Human ferritin

IgG

GST (Schistosoma japonicum)

IgG

Treponema pallidum

IgG

Horse radish peroxidase

IgG

How To Contact Us

Telephone : 031 714 6744/6700
E-mail: Martin.Bubb@nbisa.org.za

The department also manufactures a Rapidtest® Rh kit to determine the Rho status of patients. This product is ideally suited for use in an antenatal Primary Health Care setting.

Committed to providing safe, cost effective, quality products